The radiomic characteristics of CT have potential as non-invasive biomarkers for predicting Ki-67 levels in patients with lung adenocarcinoma, which might allow for a precise evaluation of tumor biological behavior, aid in clinical treatment decision making for the precise management of patients with lung adenocarcinoma, as well as provide supplemental information for depicting the heterogeneity of lung adenocarcinoma in different histological subtypes. The gene discussed is MKI67; the disease is lung adenocarcinoma.