Furthermore, we identified immune-associated patterns in BRCA1/2-MUT BC, which manifested as the recruitment of T cells, including Th1 and Tfh cells, Treg infiltration, and T cell exhaustion; these patterns would explain the critical influence on tumor progression and metastasis of BRCA1/2 mutations in BC via common and specific TME regulation patterns. The gene discussed is BRCA1; the disease is neoplasm.