BRCA1 and BRCA2 are tumor suppressor genes with critical roles in DNA damage repair; their germline or somatic mutations are closely related to carcinogenesis, including BC and high-grade serous cancer of the gynecological tract (particularly the fallopian tube, ovary, and peritoneum) (Foulkes and Shuen, 2013). This evidence concerns the gene BRCA1 and breast cancer.