Studies on the angiogenic and immune profile of murine myeloid DCs upon interaction with laminins (a family of large molecular weight glycoproteins) environments have shown that murine ovarian tumors produce several types of laminins and that DCs cultured on those laminins upregulate both AKT and MEK signaling pathways and decrease the immunological capacities, which contributes to their complicity in tumor growth (Aumailley, 2013; Phillippi et al., 2020). This evidence concerns the gene LAMB2 and ovarian neoplasm.