Further, the results of HE staining revealed that the matrix components of the TGF-β conditioned MSCs and Nalm-6 cells co-injection group had a higher tendency than those in the MSCs and Nalm-6 co-injection group and the Nalm-6 alone injection group (Figure 1F), suggesting that TGF-β conditioned MSCs might produce more matrix components to support the growth and proliferation of leukemia cells in tumor tissues. Here, TGFB1 is linked to leukemia.