KEGG pathway analysis showed that those target genes were mainly involved in endocrine resistance, breast cancer, MAPK signaling pathway, hepatitis B, viral carcinogenesis, Kaposi's sarcoma-associated herpesvirus infection, melanoma, thyroid hormone signaling pathway, non-small-cell lung cancer, chemical carcinogenesis-receptor activation, pancreatic cancer, chronic myeloid leukemia, colorectal cancer, prostate cancer, neurotrophin signaling pathway, apoptosis, estrogen signaling pathway, thyroid cancer, gastric cancer, etc. (P < 0.05; Figure 6(b)). The gene discussed is BDNF; the disease is Familial prostate cancer.