ATP13A2 and autosomal recessive spastic paraplegia type 78: Mutations in ATP13A2 typically cause Kufor-Rakeb syndrome and also a late-onset autosomal recessive spastic paraplegia 78 (SPG78) and juvenile onset amyotrophic lateral sclerosis (ALS) (50–52), whereas one family was diagnosed with CLN12 disease (14, 53, 54).