Similarly, PCSK6 abundance was upregulated in right (2.2 ± 0.2;P < 0.001) and left (1.65 ± 0.22; P < 0.05) ventricles of compensated HF rats, but to a lesser extent in decompensated subgroup (1.55 ± 0.13; P < 0.01 and 1.21 ± 0.12; P = NS, respectively), when compared with sham controls (1.0 ± 0.1 and 1.0 ± 0.05, respectively) (Figures 3N,P). Here, PCSK6 is linked to hydrops fetalis.