However, in human renal cell tumours heavily infiltrated with B cells and IgA+ plasma cells, GABA was almost exclusively detected in B cell and IgA+ plasma cell areas (Extended Data Fig. 10c), suggesting that GABA produced in the tumour microenvironment may also regulate T cells and monocytes in some settings, perhaps explaining the poor prognosis for renal cell cancers with high infiltration of B-lineage cells37. The gene discussed is CD79A; the disease is neoplasm.