Just nine genes close to these 558 variants significantly associated with T2D or HbA1c (p ≤ 2.41 × 10–5 adjusting for 2071 variant sets tested)—ANK1, GCK, HNF1A, TNRC6B, SLC30A8, NF1, IRS2, CFTR and HNF4A (Supplementary Figure 6 and Supplementary Table 32). This evidence concerns the gene CFTR and type 2 diabetes mellitus.