A linear model, controlling for batch, age, sex, and tobacco use indicated that both ALI and IPF were significantly associated with the cluster LUNG-Fib.1 expression Z-score, with IPF having a larger effect size (linear model; p = 0.017, 3.71e-19; β = 0.47, 1.63; for ALI and IPF respectively; Supplementary Table S11). This evidence concerns the gene FBL and acute respiratory distress syndrome.