PAF1 and Familial prostate cancer: To ask whether the PAF1 complex travels throughout the gene and recycles back, we performed a ChIP-seq time course for the core subunit PAF1 in the prostate cancer cell line LNCaP-abl, and monitored PAF1 distribution throughout loci before and after flavopiridol (FP) inhibition and at various time points following release from the drug.