ERBB2 and breast carcinoma: To quantify the abnormal expressions of the six circRNAs (circ_0108942, circ_0001785, circ-ERBB2, circ-BMPR2, circ-UBE2D2, circ-IRAK3) in breast cancer tissues that are reported in previous literature, the qRT-PCR results authenticated that in comparison with the HER2 Negative group, circ-ERBB2 expression was elevated in the HER2 Positive group and circ-IRAK3 was decreased, and the other four circRNAs had no remarkable changes (Fig. 1A–F).