TH and neuroblastoma: The lack of commercial antibodies able to recognize phosphorylated Drosophila TH, so we tested in human neuroblastoma cells (SH-SY5Y cells) the effect of metals on mammalian TH phosphorylation at Ser40, the major player on TH activity among the three phosphorylation sites and the only one conserved between the fly and mammals [43, 47].