A diagnosis of pSS can be made by quantifying the degree of xerostomia/xerophthalmia, a special stain for the eyes, from histologic findings of minor salivary glands, and the presence of pSS-associated autoantibodies such as anti-Ro/SSA and anti-La/SSB [7,8]. The gene discussed is SSB; the disease is Keratoconjunctivitis sicca.