Moreover, we identified the core target IL6 and other secondary targets, such as MAPK8, CXCL8, TP53, MAPK3, IL10, and CASP3, by mapping 45 junction targets, although the core therapeutic target of LHQW AKT1 did not map with the core target TNF of COVID-19. The gene discussed is TNF; the disease is COVID-19.