LEP and metabolic syndrome: The MetS component of interest in each model was included as categorical factor in the three-way interaction term, while all other MetS components (continuous variables) were treated as covariates together with cardiorespiratory fitness (CRF), body mass index (BMI), age, sex, years of education, adiponectin or leptin when one of them was included in the three-way interaction term, as well as the two-way interaction terms (i.e., adipocytokine × HOMA-IR; adipocytokine × MetS component; HOMA-IR × MetS component).