SNHG4 and gastric cancer: 2021). In gastric cancer, small nucleolar RNA host gene 4 (SNHG4) knockout upregulated the expression of miR-204-5p, resulting in an inhibitory effect on the growth of gastric cancer cells. Compared with normal gastric tissues, the expression of miR-204-5p was significantly decreased in gastric cancer tissues, and thus, SNHG4 could be used as a potential target for future treatment of tumors through the mechanism of miR-204-5p affecting tumor development (Yang et al. 2020; Cheng et al. 2021).