We additionally observed that there was a marked relation between the expression of MYL9 and the markers of Tregs and exhausted T cells including FOXP3, CCR8, CD25 (IL2RA), STAT5B, TGFβ (TGFB1), PD1 (PDCD1), CTLA4, LAG3, TIM‐3(HAVCR2), GZMB in STAD and COAD (Table S1), indicating that MYL9 had a potential role in immune escape in STAD and COAD, although further research would be needed to demonstrate the mechanisms underlying such escape. Here, CTLA4 is linked to colon adenocarcinoma.