Parents of individuals with genetically elevated apoB had a lower risk of type 2 diabetes (fathers: OR 0·88, 95% CI 0·84–0·91, FDR-adjusted p=2·3 × 10–8; mothers: 0·92, 0·88–0·97, FDR-adjusted p=0·0042), whereas the decrease in risk was weaker in siblings (0·95, 0·90–0·998, FDR-adjusted p=0·082; figure 1A). Here, APOB is linked to type 2 diabetes mellitus.