We identified weak evidence of an effect of type 2 diabetes liability on apoB in this analysis using genetic instruments derived from DIAMANTE based on the IVW and MR-Egger methods, whereas the weighted median estimate was directionally opposite to the multivariable mendelian randomisation estimate between apoB and type 2 diabetes (appendix 1 table S21). The gene discussed is APOB; the disease is type 2 diabetes mellitus.