Bioinformatics analysis of miR-182-5p revealed that EPAS1, PRKCE (protein kinase C epsilon), NR3C1 (nuclear receptor subfamily 3 group C member 1), and RHOB are the primary genes in the protein-protein interaction (PPI) network of lung squamous cell carcinoma 18. The gene discussed is EPAS1; the disease is squamous cell lung carcinoma.