PRKCD and gastric cancer: Quercetin has been proven to induce antimetastatic effects in gastric cancer cells by suppressing the uPA/uPAR system via modulation of various associated pathways, including the NF-κb, PKC-δ, ERK1/2, and AMPKα pathways, indicating that uPAR may be a potential target for the treatment of gastric cancer 161.