The high expression of MUC1 was significantly associated with the level of CA19-9 (P < 0.05), AFP (P < 0.05), and more aggressive tumor phenotypes including larger tumor size (P < 0.05), presence of lymph node metastases (P <0.05), vascular infiltration (P < 0.05), and advanced TNM stage (P < 0.05) (Table 1). The gene discussed is AFP; the disease is neoplasm.