KIR3DL1 and hepatocellular carcinoma: Our results showed that: (1) there was no detectable association of KIR-HLA genotype with liver cirrhosis development, (2) patients with KIR2DS3 had a significantly higher risk of HCC, with no remarkable involvement of any KIR/HLA pair, and (3) patients with the KIR3DL1/HLA-Bw4 pair were significantly more likely to achieve freedom from NUCs.