With respect to omentin significant decrease was observed only comparing HOMA-IR ≤ 3 COVID-19 subgroup with healthy volunteers (399.7 [261.7–566.7] vs. 814.3 [435.3–1148.5] ng/ml; p = 0.01), while there was no difference with respect to COVID-19 patients with HOMA-IR > 3 and control group (593.8 [436.7–706.2] vs. 814.3 [435.3–1148.5] ng/ml; p = 0.10). This evidence concerns the gene ITLN1 and COVID-19.