Though “TRAP control versus PARIS WT” and “PARIS mutant versus PARIS WT” pairwise comparisons separately support this conclusion (in broad terms), as a caveat of our approach this previously observed expression pattern (i.e. transcriptionally suppressed in PARIS WT and restored back to normal levels in PARIS mutant fly lines) to describe the phenotypic changes in PD models could not form a significant cluster due to the presumably low number of DEGs with this expression profile identified in the 3-group comparison (Supplementary Fig. 23). The gene discussed is ZNF746; the disease is Parkinson disease.