Finally, KEGG pathway and “Associated Disease” inferences from DAVID analysis with the human orthologs of the DEGs identified from “TRAP control versus PARIS WT” pairwise comparison taken as input highlighted PD and mitochondrial functioning as the top deregulated signaling pathways, and the neurological and the psychiatric disorders as the underlying disease networks (Table 2, Supplementary Figs. 9–10). The gene discussed is ZNF746; the disease is Parkinson disease.