DDX41 and COVID-19: By our recently established rapid neutralizing Abs screening system23, we have successfully obtained 20 neutralizing Abs with high affinities to RBD from COVID-19 convalescent individuals, and their neutralizing potency was confirmed by the half inhibition concentrations (IC50s) against authentic SARS-CoV-2 virus quantified via qRT-PCR (Fig. 1a, c and Supplementary Fig. 1).