Given that PRMT1 is overexpressed37 and USP11 is dysregulated in breast cancer38, and that the MCF7 breast cancer cell line expresses high levels of PRMT1 and USP11 (Supplementary Fig. 1c), we also tested the ability of PRMT1 to methylate USP11 in this cell line. The gene discussed is USP11; the disease is breast cancer.