Interestingly, two other de novo mutations in LGALS3BP were identified in a cohort of individuals with autism spectrum disorder and a cohort with schizophrenia61,62, and together with the fact that LGALS3BP is found in the recently developed SZDB database63 and it is detected in the serum proteomes of patients with schizophrenia it suggests its potential contribution to the development of such disorders64. The gene discussed is LGALS3BP; the disease is schizophrenia.