We found that proBDNF and p75NTR protein levels significantly increased in hippocampus after 7 (proBDNFp < 0.05, p75NTRp < 0.01, Fig. 9a), 14 (proBDNFp < 0.05, p75NTRp < 0.05 Fig. 9b), and 28 (proBDNFp < 0.05, p75NTRp < 0.01, Fig. 9c) days of meningitis induction, compared with rats in the sham group. Here, BDNF is linked to meningitis.