Many probe sets that were identified interrogate genes that have already been associated with AML, including CEBPD, PBX3, DUSP6, LILR2, HGF, FSCN1, TNFSF10, RUNX1T1, HOXB3, TAL1, SLC40A1, and CLEC11A. CEBPD is thought to be a tumor suppressor gene, given it is commonly hypermethylated in AML and thus results in low CEBPD expression [22]. The gene discussed is RUNX1T1; the disease is acute myeloid leukemia.