For predicting severe AP, the accuracy of PEV was significantly higher than that of CRP levels (p < .0001), BISAP scores (p = .0052), Marshall scores (p < .0001), CTSI scores (p < .0001), and EPIC scores (p < .0001), and its accuracy was similar to that of the Ranson scores (p = .0648). This evidence concerns the gene CRP and alkaline phosphatase measurement.