Of note, the perturbation of the liver damage parameters ALT, AST, total bilirubin, and also MDP values of IL-4, IL-6, IL-8, IL-12p70, CXCL9, CCL5, CCL2, CRP, fibrinogen and parasitemia levels showed an inverse correlation with the time living in the endemic area. This evidence concerns the gene CRP and parasitic infectious disease.