Only 12.6% of our study population would have been eligible to participate in the DiRECT trial because exclusion criteria were people aged >65 years at diagnosis of diabetes (29.8% of our population), people with a duration of type 2 diabetes >6 years (63.7% of our population), people with BMI >45 kg/m2 or <27 kg/m2 (4.9% of our population), previous insulin use (7.9% of our population), and HbA1c ≥108 mmol/mol at diagnosis (1.5% of our population). Here, INS is linked to diabetes mellitus.