Foxp3DTR CML mice with comparable leukemia burden (37 ± 8 BCR-ABL1-GFP+Gr-1+ granulocytes; [L-Gr-1+ cells]/μL blood) were randomized to control treatment with vehicle or DT for Treg depletion 13 days after leukemia transplantation (Figure 3A). The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.