FACS analysis revealed that — besides CD4+Foxp3+ Tregs, also a fraction of CD8+ CTLs — CD4+Foxp3– T cells, L-Gr-1+ cells, and LSCs express Tigit in the BM of CML mice (Supplemental Figure 4, D and E). The gene discussed is CD8A; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.