Importantly, the expression of FOXP3 mRNA strongly correlated with TNFRSF4 and TGFB1 in the BM of CML patients but not in healthy donor control BM (Figure 8, L and M, and Supplemental Figure 5, E and F). The gene discussed is TNFRSF4; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.