We also used the GEPIA database (http://gepia.cancer-pku.cn/index.html) to investigate whether RPS6KB1 expression levels correlated with the prognosis of cancer patients, and fount that RPS6KB1 expression levels significantly impacted the prognosis of seven types of cancer, including breast, lung, ovarian and liver cancers (Figure 5B). This evidence concerns the gene RPS6KB1 and liver cancer.