INS and Hypoglycemia: Compared with the first episode of severe hypoglycemia, recurrent episodes (≥2) were associated with only modestly higher odds of deintensification, and those higher odds were observed only among individuals receiving sulfonylurea only (AOR, 1.10; 95% CI, 1.03-1.17) or sulfonylurea in combination with insulin (AOR, 1.09; 95% CI, 1.01-1.18).