In addition, the upregulation of FURIN in HNSCC/OSCC in the background of unchanged ACE2 mRNA is less likely to amplify the risk for SARS‐CoV‐2 attachment, as the pre‐primed S‐protein requires ACE2 binding for the cellular entry (Shang et al., 2020). This evidence concerns the gene ACE2 and head and neck squamous cell carcinoma.