Clumping factor A (ClfA) is the most extensively studied SDR protein and is known to be involved in triggering sepsis (Flick et al., 2013 ▸; McAdow et al., 2011 ▸; Higgins et al., 2006 ▸; Loof et al., 2015 ▸). The gene discussed is CAVIN2; the disease is Sepsis.