Moreover, tumour cell‐derived exosomes can regulate biological characteristics and signalling pathways of recipient cells, and reshape the tumour microenvironment through a delivery of multiple targeted molecules including recombinant lysyl oxidase‐like protein 4 (LOXL4), miR‐122 and miR‐222‐3p.34, 35, 36, 37. The gene discussed is LOXL4; the disease is neoplasm.