FOLH1 and posterior cortical atrophy: In a comparative study, [68 Ga]PSMA-11 PET/computed tomography (CT)-guided biopsy detected more clinically “significant PCa” (sigPCa) than ultrasound (US)-guided biopsy [9], reaching a high per-patient accuracy of 81–93% for [68 Ga]- or [18F]PSMA PET-guided biopsy, with a slightly lower lesion-based accuracy ranging between 70 and 80% [10, 11].