Their inflammation levels, including CRP, interleukin-6 (IL-6), and erythrocyte sedimentation rate (ESR), were measured using questionnaires to assess the activity of RA such as the Health Assessment Questionnaire (HAQ), visual analogue scale (VAS), and Disease Activity Score (DAS) 28; liver and kidney functions were compared between two groups. This evidence concerns the gene CRP and rheumatoid arthritis.