Moreover, Ad-Runx1, which was injected into the left ventricle of MI rats, could offset the cardioprotective effect of dihydrolycorine, as characterized by increased in LVEDD and LVESD and decreased LVEF and LVFS compared to the MI+dihydrolycorine+Ad-EV group (Table 2). This evidence concerns the gene RUNX1 and myocardial infarction.