We found a number of genes that were upregulated specifically in the interface cluster relative to both tumor and muscle, including, interestingly, a number of uncharacterized genes, genes related to increased transcriptional/translational activity (atf3, eif3ea, and ribosomal genes), and genes related to the microtubule cytoskeleton (tuba1a and tuba1c) (Fig. 2c and Supplementary Data). Here, ATF3 is linked to neoplasm.