The authors also demonstrated that in neonatal mice the presence of RORγt+ γδ T cells, which produce IL-17, were resistant to CDI while the depletion of these cells abrogated the protective effect.101 Markey et al. 102 showed that pre-colonization with commensal Candida albicans protects against lethal CDI. Here, IL17A is linked to clostridium difficile infection.