IFITM3 and cancer: In intact epithelial cells, four proteins associated with EGFR in the vicinity of C. albicans hyphae: WW domain-binding protein 2 (WBP2), which governs EGFR expression and signaling in cancer cells; Toll-interacting protein (TOLLlIP), which is a negative regulator of Toll-like receptor signaling; interferon-induced transmembrane protein 3 (IFITM3), which is an antiviral protein; and the globular C1q receptor (gC1qR), which is a multifunctional protein that interacts with a variety of serum components.