AptNCL-SLUGsiR- and aptNCL-NRP1siR-mediated suppression of SLUG and NRP1, respectively, can decrease cell growth, motility, invasiveness, and angiogenesis of only NCL-expressing cancer cells which demonstrates that synergistic suppression of lung cancer can be achieved using a combination of both aptamer-siRNA chimeras [96]. This evidence concerns the gene SNAI2 and lung carcinoma.