TP53 and medulloblastoma: This hypothesis gains support from two recent studies in which retroviral gene-trap and functional characterization of primary mouse astrocyte clones under p53–/– background found that STOX1A was one of the top two altered proteins [15] and STOX1A was a transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation [14].