In recent years, the third-generation EGFR-TKI osimertinib, which targets both EGFR-sensitive mutations and T790M-resistant mutation, has showed efficacy superior to other EGFR-TKIs in NSCLC patients with EGFR T790M-resistant mutation [10] or with EGFR-sensitive mutations [11, 12] and is widely adopted as first-line treatment in current clinical practice. Here, EGFR is linked to non-small cell lung carcinoma.