Besides the clinicopathological and hematological evaluations [7,8], this study aimed to explore the correlation of IVM-induced oxidative stress and cutaneous bovine papillomas regression through the estimation of oxidative stress markers; malondialdehyde (MDA), glutathione reduced (GSH), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) [9]. The gene discussed is SOD1; the disease is papilloma.