CACNA2D1 and Familial short QT syndrome: In addition, several other genes associated with BrS are also associated with other cardiac pathologies, as previously reviewed elsewhere (202), such as PKP2, DSC2, JUP, DSG2, and RYR2 in ARVC (108, 202), SCN1B and CACNA1C in LQTS, CACNA1C, CACNA2D1, and CACNB2 in short QT syndrome, and CACNA1C, CACNA2D1, CACNB2, HCN4, and KCNJ8 in early repolarization syndrome (202).